Search results for " Enterobacteriaceae"

showing 10 items of 12 documents

Antibiotic treatment of infections caused by carbapenem-resistant Gram-negative bacilli: an international ESCMID cross-sectional survey among infecti…

2018

ESGAP, ESGBIS, ESGIE and the CRGNB treatment survey study group.

0301 basic medicineAcinetobacter baumanniiCarbapenemAntibioticsDrug ResistanceDrug resistanceTigecyclineAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; SurveyPolymyxin0302 clinical medicineSurveys and Questionnairespolycyclic compounds030212 general & internal medicineAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; Survey; Anti-Bacterial Agents; Carbapenems; Cross Infection; Cross-Sectional Studies; Drug Resistance Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals; Humans; Microbial Sensitivity Tests; Surveys and QuestionnairesSurveyCarbapenemAcinetobacter baumannii; Carbapenem; Carbapenem-resistant Gram-negative bacilli; Combination therapy; Enterobacteriaceae; Polymyxin; Pseudomonas aeruginosa; Survey; Anti-Bacterial Agents; Carbapenems; Cross Infection; Cross-Sectional Studies; Drug Resistance Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals; Humans; Microbial Sensitivity Tests; Surveys and Questionnaires; Microbiology (medical); Infectious DiseasesCross InfectionbiologyMicrobial Sensitivity TestCarbapenem-resistant Gram-negative bacilliBacterialantibiotic management carbapenem-resistant Gram-negative bacteriaGeneral MedicineHospitals3. Good healthAcinetobacter baumanniiAnti-Bacterial AgentsInfectious DiseasesPseudomonas aeruginosamedicine.drugHumanMicrobiology (medical)medicine.medical_specialtymedicine.drug_class030106 microbiologyMicrobial Sensitivity TestsFosfomycincarbapenem-resistant Gram-negative bacteria03 medical and health sciencesHospitalEnterobacteriaceaeInternal medicineAnti-Bacterial AgentDrug Resistance BacterialGram-Negative BacteriamedicineGram-Negative Bacterial InfectionHumansCombination therapyCross-Sectional Studiebusiness.industrybiochemical phenomena metabolism and nutritionbiology.organism_classificationbacterial infections and mycosesCross-Sectional StudiesCarbapenemsInfectious disease (medical specialty)Carbapenem-resistant gram-negative bacilli[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieantibiotic managementbusinessGram-Negative Bacterial InfectionsRifampicin
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Ceftazidime-Avibactam Combination Therapy Compared to Ceftazidime-Avibactam Monotherapy for the Treatment of Severe Infections Due to Carbapenem-Resi…

2020

Ceftazidime-avibactam (CZA) is a novel beta-lactam beta-lactamase inhibitor combination approved for the treatment of complicated urinary tract infections, complicated intra-abdominal infections, and for hospital-acquired/ventilator-associated pneumonia. The aim of this systematic review (PROSPERO registration number: CRD42019128927) was to evaluate the effectiveness of CZA combination therapy versus CZA monotherapy in the treatment of severe infections. The databases included in the search, until February 12th, 2020, were MEDLINE by PubMed, EMBASE, and The Cochrane Central Register of Controlled Trials. We included both randomized controlled trials (RCTs) and non-randomized studies publish…

0301 basic medicineCarbapenem-resistant enterobacteriaceaeBiochemistrylaw.inventionsepsisCeftazidime‐avibactam0302 clinical medicineRandomized controlled trialsystematic reviewlawPharmacology (medical)030212 general & internal medicineGeneral Pharmacology Toxicology and Pharmaceuticsnetwork meta-analysisceftazidime-avibactamAnti‐infective agentnetwork meta-analysiInfectious Diseasescarbapenem-resistant EnterobacteriaceaeMeta-analysisβ-lactamase inhibitors.sepsimedicine.drugMicrobiology (medical)medicine.medical_specialtyCombination therapyβ-lactamase inhibitors030106 microbiologyMEDLINEβ‐lactamase inhibitorsMicrobiologyArticle03 medical and health sciencesCarbapenem‐resistant Enterobacteriaceaemultidrug resistanceInternal medicinemedicineanti-infective agentbacteremiabusiness.industrylcsh:RM1-950Retrospective cohort studyCeftazidime/avibactammedicine.diseaseinfectionlcsh:Therapeutics. PharmacologyBacteremiaanti-infective agentsbusinessNetwork meta‐analysi
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Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone

2017

ABSTRACT : The global spread of Klebsiella pneumoniae producing Klebsiella pneumoniae carbapenemase (KPC) has been mainly associated with the dissemination of high-risk clones. In the last decade, hospital outbreaks involving KPC-producing K. pneumoniae have been predominantly attributed to isolates belonging to clonal group (CG) 258. However, results of recent epidemiological analysis indicate that KPC-producing sequence type (ST) 307, is emerging in different parts of the world and is a candidate to become a prevalent high-risk clone in the near future. Here we show that the ST307 genome encodes genetic features that may provide an advantage in adaptation to the hospital environment and t…

0301 basic medicineSettore MED/07 - Microbiologia E Microbiologia Clinicasiderophoreantibiotic resistancelong term survivalsequence analysisKlebsiella pneumoniaepolymerase chain reactionResponses to Human InterventionsDrug ResistanceGene TransferClone (cell biology)ST259bacterial proteinvirulence factorYersiniabactinGenomechemistry.chemical_compoundMicrobialPlasmidAntibioticsbacterial genomepathogenicitygenetics610 Medicine & healthgenome analysisCross InfectionMolecular EpidemiologyGenomeVirulencebiologydrug effectyersiniabactinBacterialDrug Resistance MicrobialGeneral MedicineKlebsiella infectionglycogen synthesisKlebsiella pneumoniaeEnglandItalyST307horizontal gene transferProteínas BacterianasResearch ArticleGene Transfer HorizontalVirulence FactorsSequence analysiscapsule030106 microbiologyVirulence610 Medicine & healthpulsed field gel electrophoresisColombiaCarbapenemase; siderophore; yersiniabactin; bacterial protein; beta lactamase; virulence factor antibiotic resistance; Article; bacterial strain; bacterial virulence; bacterium isolate; fimbria; genome analysis; glycogen synthesis; Klebsiella pneumoniae; long term survival; microbial diversity; nonhuman; plasmid; polymerase chain reaction; pulsed field gel electrophoresis; sequence analysis; whole genome sequencing; antibiotic resistance; bacterial genome; carbapenem-resistant Enterobacteriaceae; Colombia; cross infection; drug effect; England; genetic variation; genetics; horizontal gene transfer; human; Italy; Klebsiella infection; microbiology; molecular epidemiology; multilocus sequence typing; pathogenicity; virulence Bacterial Proteins; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Colombia; Cross Infection; Drug Resistance Microbial; England; Gene Transfer Horizontal; Genetic Variation; Genome Bacterial; Humans; Italy; Klebsiella Infections; Klebsiella pneumoniae; Molecular Epidemiology; Multilocus Sequence Typing; Virulence; Virulence Factors; Whole Genome SequencingArticlebeta-Lactamasesbeta lactamaseHorizontalMicrobiologyCarbapenemase03 medical and health sciencesAntibiotic resistanceBacterial ProteinsplasmidHumanshumanInfecciones por KlebsiellafimbrianonhumanWhole Genome Sequencingbacterial virulencebacterium isolatemicrobiologyGenetic Variationbacterial strainbiology.organism_classificationKlebsiella InfectionsEnterobacteriaceae Resistentes a los CarbapenémicosKPCCarbapenem-Resistant Enterobacteriaceae030104 developmental biologychemistrymicrobial diversityEpidemiología MolecularGenome BacterialWGSMultilocus Sequence Typing
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Enteric bacteria of food ice and their survival in alcoholic beverages and soft drinks

2017

This study aimed to evaluate the levels of enteric bacteria in ice cubes produced in different environments (home-made, prepared in bars and pubs with ice machines and produced in industrial plants) and to determine their survival in different alcoholic beverages and soft drinks. Members of the Enterobacteriaceae family were found in almost all samples analysed. All industrial and the majority of home-made samples did not contain coliforms. Enterococci were not identified in domestic samples while they were detected in two industrial and three bar/pub samples. The samples collected from bars and pubs were characterized by the highest levels of enteric bacteria. Fourteen strains representing…

0301 basic medicineSurvivalPantoea conspicua030106 microbiologyEnteric bacteriaCarbonated BeveragesFood ContaminationMicrobiology03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoEnterobacteriaceaeSoft drinkFood scienceCarbonated BeverageColiformAlcoholic beverageMicrobial ViabilitybiologyAlcoholic BeveragesIceIce cubeHygienebiology.organism_classificationEnterobacteriaceaeEnterococcuStenotrophomonas maltophiliaEnterococcusStenotrophomonasAlcoholic beverages; Coliforms; Enterobacteriaceae; Enterococcus; Hygiene; Ice cubes; Soft drinks; Survival; Alcoholic Beverages; Carbonated Beverages; Enterobacteriaceae; Food Contamination; Ice; Microbial Viability; Food Science; MicrobiologyEnterococcus faeciumFood ScienceSettore AGR/16 - Microbiologia Agraria
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Outbreak of IMI-1 Carbapenemase-producing colistin-resistant Enterobacter cloacae on the French island of Mayotte (Indian Ocean)

2018

International audience; The spread of carbapenemase-producing Enterobacteriaceae in the Southwest Indian Ocean islands is poorly known. Here we describe an outbreak of colistin-resistant Enterobacter cloacae harbouring blaIMI-1 in the French overseas department of Mayotte. Between October 2015 and January 2017, all isolates of imipenem-non-susceptible E. cloacae at Mayotte Medical Center and University Hospital of Reunion Island were screened for carbapenemase production. Positive isolates were typed by pulsed-field gel electrophoresis and whole-genome sequencing (WGS)-based multilocus sequence typing (MLST), and all β-lactamase genes were identified by PCR and sequencing. Resistance profil…

Male0301 basic medicineImipenembla(IMI-1)Carbapenem-resistant enterobacteriaceaeComorosDisease Outbreaks[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyPharmacology (medical)Enterobacteriaceae InfectionsGeneral MedicineMiddle AgedFrench overseas islandAnti-Bacterial AgentsElectrophoresis Gel Pulsed-Field3. Good healthInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyFemalemedicine.drugAdultErtapenemMicrobiology (medical)Adolescent030106 microbiologyMayotteMicrobial Sensitivity TestsBiologybeta-LactamasesMicrobiologyCarbapenemaseYoung Adult03 medical and health sciencesBacterial Proteins[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyEnterobacter cloacaePulsed-field gel electrophoresismedicineHumansEtestColistinOutbreakOutbreakbiology.organism_classificationCephalosporinsImipenemCarbapenem-Resistant EnterobacteriaceaeCarbapenemsColistinMultilocus sequence typingEnterobacter cloacaeGenome BacterialMultilocus Sequence Typing
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Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia

2020

N.J.S. is partially funded by the Department of Veterans Affairs, Quality Enhancement Research Initiative (QUERI) Partnered Evaluation Initiative Grant (HX002263-01A1). Background and objective : Enterobacteriaceae (EB) spp. family is known to include potentially multidrug-resistant (MDR) microorganisms, and remains as an important cause of community-acquired pneumonia (CAP) associated with high mortality. The aim of this study was to determine the prevalence and specific risk factors associated with EB and MDR-EB in a cohort of hospitalized adults with CAP. Methods : We performed a multinational, point-prevalence study of adult patients hospitalized with CAP. MDR-EB was defined when ≥3 ant…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtycommunity-acquired pneumoniaCommunity-acquired pneumoniaEnterobacteriaceae ; community-acquired pneumonia ; multidrug-resistance ; prevalence ; risk factorsInternational CooperationprevalenceMultidrug-resistanceMicrobial Sensitivity TestsSettore MED/10 - Malattie Dell'Apparato RespiratorioResearch initiativeE-NDASCohort StudiesCommunity-acquired pneumoniaSDG 3 - Good Health and Well-beingEnterobacteriaceaePrevalenceHumansMedicinerisk factorsIn patientRisk factorVeterans Affairshealth care economics and organizationsAgedbusiness.industryEnterobacteriaceae InfectionsQR Microbiologymedicine.diseasecommunity-acquired pneumonia; Enterobacteriaceae; multidrug-resistance; prevalence; risk factorsmultidrug-resistanceDrug Resistance MultiplehumanitiesQuality enhancementQRCommunity-Acquired InfectionsHospitalizationRisk factorsrisk factorFamily medicineFemalebusinessRisk assessmentCohort study
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Characterization of Carbapenem-Resistant Enterobacteriaceae Clinical Isolates in Al Thawra University Hospital, Sana'a, Yemen

2020

International audience; Objective: The aim of this study was to investigate the resistance mechanisms of carbapenem-resistant Enterobacteriaceae clinical strains recovered from Al Thawra University Hospital, Sana'a, Yemen. Methods: A total of 27 isolates showing decreased susceptibility to carbapenems were obtained from different clinical specimens in Al Thawra Hospital, Sana'a, Yemen. Strains were identified by Matrix Assisted Laser Desorption Ionization Time-Of-Flight spectroscopy. Susceptibility to antibiotics was determined by the disk diffusion method on Mueller Hinton agar. Carbapenemases-encoding genes, extended-spectrum β-lactamases (ESBLs), and plasmid-mediated quinolone resistance…

MaleYemenKlebsiella pneumoniaeGene ExpressionCarbapenem-resistant enterobacteriaceaeQuinolonesmedicine.disease_causeHospitals Universitychemistry.chemical_compoundChildEscherichia coli InfectionsAged 80 and over0303 health sciencesbiologyEnterobacteriaceae InfectionsMiddle AgedEnterobacteriaceae3. Good healthAnti-Bacterial AgentsBacterial Typing TechniquesMueller-Hinton agarKlebsiella pneumoniae[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyNDM-1-likeChild PreschoolFemalePlasmidsMicrobiology (medical)AdultcarbapenemasesImmunologyMicrobial Sensitivity TestsMicrobiologybeta-Lactam Resistancebeta-LactamasesMicrobiology03 medical and health sciencesEnterobacteriaceaeEnterobacter cloacaemedicineEscherichia coliHumansTypingEscherichia coli030304 developmental biologyAgedPharmacology030306 microbiologyInfantbiochemical phenomena metabolism and nutritionbiology.organism_classificationClone CellsKlebsiella InfectionsCarbapenem-Resistant EnterobacteriaceaechemistryCarbapenemsMultilocus sequence typingbacteriaEnterobacter cloacaeMultilocus Sequence TypingOXA-48-like
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Healthcare-Associated Pneumonia and Multidrug Resistant Bacteria: Do We Have a Convincing Answer?

2014

Methicillin-Resistant Staphylococcus aureusMicrobiology (medical)medicine.medical_specialtyBacteriabusiness.industryMedicine (all)Drug ResistanceBacterialPneumonia Ventilator-AssociatedBacteria; Enterobacteriaceae; Humans; Methicillin-Resistant Staphylococcus aureus; Pneumonia Ventilator-Associated; Pseudomonas aeruginosa; Drug Resistance Bacterial; Infectious Diseases; Microbiology (medical); Medicine (all)Pneumoniamedicine.diseasePneumoniaVentilator-AssociatedMultidrug resistant bacteriaInfectious DiseasesHealthcare associatedEnterobacteriaceaeDrug Resistance BacterialPseudomonas aeruginosamedicineBacteria; Enterobacteriaceae; Humans; Methicillin-Resistant Staphylococcus aureus; Pneumonia; Ventilator-Associated; Pseudomonas aeruginosa; Drug Resistance; Bacterial; Infectious Diseases; Microbiology (medical); Medicine (all)HumansIntensive care medicinebusiness
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Profiling of Protein Degraders in Cultures of Human Gut Microbiota

2019

Unabsorbed proteins reach the colon and are fermented by the microbiota, yielding a variety of harmful metabolites. In the present study, a 16S rRNA gene survey identified the bacterial taxa flourishing in 11 batch fermentations with proteins and peptones as the sole fermentable substrates, inoculated with the feces of six healthy adults. Organic acids, ammonia, and indole resulting from protein breakdown and fermentation accumulated in all of the cultures. Analysis of differential abundances among time-points identified Enterobacteriaceae, Burkholderiaceae, and Desulfovibrionaceae (including Esherichia-Shigella, Sutterella, Parasutterella, and Bilophila) among the bacteria that especially …

Microbiology (medical)proteolysisFirmicuteslcsh:QR1-502gut microbiota proteolysis metagenomics enrichment culture EnterobacteriaceaeSutterellaMicrobiologylcsh:MicrobiologyMicrobiology03 medical and health sciencesEnterobacteriaceaeenrichment culture030304 developmental biologyOriginal Research0303 health sciencesmetagenomicsbiologygut microbiota030306 microbiologyRuminococcusLachnospiraceaeBacteroidetesbiology.organism_classificationRoseburiaBacteroidesRuminococcaceaeFrontiers in Microbiology
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Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo.

2011

International audience; BACKGROUND AND OBJECTIVES: Interaction of bacteria with the immune system within the intestinal mucosa plays a key role in the pathogenesis of inflammatory bowel disease (IBD). The aim of the current study was to develop a fluorescein-aided confocal laser endomicroscopy (CLE) method to visualise intramucosal enteric bacteria in vivo and to determine the involved mucosal area in the colon and ileum in patients with ulcerative colitis (UC) and Crohn's disease (CD). METHODS: Initially, E coli strains expressing enhanced green fluorescent protein (pEGFP) were endomicroscopically imaged in mice. In addition, ex vivo and in vivo imaging of fluorescent human enteric bacteri…

PathologyMESH : Escherichia colifluoresceinMESH : Retrospective StudiesColorectal cancerMESH : Prospective StudiesGastroenterologyInflammatory bowel disease[ SDV.CAN ] Life Sciences [q-bio]/Cancer0302 clinical medicineIntestinal mucosaMESH: Microscopy ConfocalMESH: AnimalsMESH : Colonoscopy1506MESH: In Situ Hybridization Fluorescenceintramucosal bacteria0303 health sciencesCrohn's diseaseMESH: Escherichia coliGastroenterologyMESH : EnterobacteriaceaeMESH : Colitis UlcerativeUlcerative colitisenteric bacterial microflora3. Good healthMESH : In Situ Hybridization FluorescenceCrohn's diseaseMESH: Colonoscopyconfocal laser endomicroscopyMESH: Intestinal MucosaMESH : Inflammatory Bowel Diseases030211 gastroenterology & hepatologymedicine.medical_specialtyMESH : MaleMESH: Colitis Ulcerative[SDV.CAN]Life Sciences [q-bio]/CancerMESH : Mice Inbred C57BLBiologyMESH : Intestinal MucosaMESH : Crohn Disease03 medical and health sciencesMESH: EnterobacteriaceaeFISHfluorescence endoscopyIn vivoMESH: Mice Inbred C57BLInternal medicineMESH : MicemedicineEndomicroscopyMESH: ColonMESH : Microscopy ConfocalMESH: Miceulcerative colitis030304 developmental biologyMESH : IleumMESH: HumansBacteriaMESH: Crohn Diseaseinfectious colitisMESH : HumansEndoscopyMESH: Retrospective Studiesmedicine.diseaseMESH: Inflammatory Bowel DiseasesMESH : ColonMESH: MaleMESH: Prospective StudiesMESH: IleumMESH : AnimalsEx vivo
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